She wasn't Shane
Clue: Eric Knight touched hearts with the 1940 novel imploring this dog to "come home".
Answer: "What is Lassie?"
NO! It wasn't "Lassie, come home" - imploring her - it was "Lassie Come-Home" - a phrase for a dog that came home after it was sold, a form of cheating the buyer. In fact, the boy Joe was made to tell her NOT to come home (though it didn't stop her).
Note the hyphen on the book jacket. Yes, the movie dropped that, but the clue was about the novel.
Alex, your clue is WRONG.